DIMENSIONALITY REDUCTION INCONTROL AND COORDINATION OF HUMAN HAND

The human hand is an excellent example of versatile architecture which can easily accomplish numerous tasks with very least effort possible. Researchers have been trying to analyze the complex architecture of the human hand. It is an unsolved mystery even today how Central Nervous System (CNS) controls the high degree of freedom (DoF) of the human hand. Investigators have put forth numerous theories which support movement planning both at higher and lower levels of the neural system as well as the bio mechanical system. This planning is hypothesized to happen in a reduced dimensionality space of tiny modules of movement called movement primitives often referred to as synergies. These synergies are physiologically significant in planning and control of movement.This dissertation presents time-varying kinematic synergies which linearly combine to generate the entire movement. The decomposition of these synergies becomes an exciting optimization problem and even more fascinating as it addresses two most important problems of motor control—coordination and dimensionality reduction. In this dissertation, a new model of convolutive mixtures for generation of joint movements is proposed. According to this model, an impulse originated in the higher-level neural system evokes the activation of some circuits in the lower-level neural system, then stimulates certain biomechanical structures, and eventually creates a stereotyped angular change at each finger-joint of the hand. Current model enabled greater access to existing blind source separation algorithms which reduce the computational complexity. First, kinematic synergies were extracted from a well known matrix factorization method, namely principal component analysis. By using the above kinematic synergies, a method to obtain temporal postural synergies is established. These temporal postural synergies were further used in the model of convolutive mixtures. An optimal selection of these temporal synergies which can reconstruct movements is then achieved by l1-minimization. The realization of the model by l1-minimization out performed the previous models which use steepest descent gradient methods. Synergies have received increased attention in the fields of robotics, human computer interface, telesurgery and rehabilitation. Improved performance and new computational model to decompose synergies presented here might enable them to be appropriate for real time applications

Biomimetic Prosthetics

Biomimetic prosthetics are advanced devices that mimic the physical and functional properties of the replaced limb, thus restoring near-natural form and function. This flourishing field of research will continue to play an important role in improving quality of life, independence, and community participation for individuals with disabilities. This humble compilation showcases a few representative examples of progress in this exciting field

Reconstructing Synergy-Based Hand Grasp Kinematics from Electroencephalographic Signals

Brain-machine interfaces (BMIs) have become increasingly popular in restoring the lost motor function in individuals with disabilities. Several research studies suggest that the CNS may employ synergies or movement primitives to reduce the complexity of control rather than controlling each DoF independently, and the synergies can be used as an optimal control mechanism by the CNS in simplifying and achieving complex movements. Our group has previously demonstrated neural decoding of synergy-based hand movements and used synergies effectively in driving hand exoskeletons. In this study, ten healthy right-handed participants were asked to perform six types of hand grasps representative of the activities of daily living while their neural activities were recorded using electroencephalography (EEG). From half of the participants, hand kinematic synergies were derived, and a neural decoder was developed, based on the correlation between hand synergies and corresponding cortical activity, using multivariate linear regression. Using the synergies and the neural decoder derived from the first half of the participants and only cortical activities from the remaining half of the participants, their hand kinematics were reconstructed with an average accuracy above 70%. Potential applications of synergy-based BMIs for controlling assistive devices in individuals with upper limb motor deficits, implications of the results in individuals with stroke and the limitations of the study were discussed

Dynamical Synergies of Multidigit Hand Prehension

Hand prehension requires highly coordinated control of contact forces. The high-dimensional sensorimotor system of the human hand operates at ease, but poses several challenges when replicated in artificial hands. This paper investigates how the dynamical synergies, coordinated spatiotemporal patterns of contact forces, contribute to the hand grasp, and whether they could potentially capture the force primitives in a low-dimensional space. Ten right-handed subjects were recruited to grasp and hold mass-varied objects. The contact forces during this multidigit prehension were recorded using an instrumented grip glove. The dynamical synergies were derived using principal component analysis (PCA). The contact force patterns during the grasps were reconstructed using the first few synergies. The significance of the dynamical synergies, the influence of load forces and task configurations on the synergies were explained. This study also discussed the contribution of biomechanical constraints on the first few synergies and the current challenges and possible applications of the dynamical synergies in the design and control of exoskeletons. The integration of the dynamical synergies into exoskeletons will be realized in the near future